Amway, 安利

文章标题：通过抗氧化和促生存机制，一种新的植物配方(纽崔莱葆明配方）可以缓解光诱导的视网膜损伤

摘要内容：在全世界范围内，光引起的眼疲劳变得越来越普遍。现代社会迫切需要有效的视网膜光损伤治疗方案。我们研究了由叶黄素酯、玉米黄质、菊花、枸杞和黑加仑提取物组成的新配方对视网膜损伤的影响。本研究中，我们同时诱导了体内和体外导致的视网膜光损伤模型。

通过抗氧化和促生存机制，我们的植物配方可以缓解视网膜的光损伤

该论文发表于国际营养学期刊《氧化医学和细胞寿命》第 2020 卷 | 第 7676818 条

整篇论文请去安利头条 App—下载专区下载

在全世界范围内，强光引起的视疲劳变得越来越普遍。为了确证葆明配方能够保护我们的双眼，纽崔莱健康研究院开展了一项体内实验，证明由叶黄素酯、玉米黄质、菊花、枸杞和黑加仑提取物组成的葆明配方能够减少视网膜组织受到强光刺激引起的损伤。由于验证功效的同时成功阐明了葆明配方对于细胞的分子保护机制，纽崔莱健康研究院阚君陶博士在影响因子高达5.076的OxidativeMedicineandCellularLongevity杂志发表以下论文。六年潜心研究，只为给你呈上最优质的营养。

KanJ,ChengJ,GuoJ,etal.Anovelbotanicalcombinationattenuateslight-inducedretinaldamagethroughantioxidantandprosurvivalmechanisms[J].

Oxidativemedicineandcellularlongevity,2020（2020），ArticleID7676818.

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Hindawi

Oxidative Medicine and Cellular Longevity

Volume 2020, Article ID 7676818, 8 pages

https://doi.org/10.1155/2020/7676818

通过抗氧化和促生存机制，一种新的植物配方（纽崔莱葆明配方）可以缓解光诱导的视网膜损伤

Research Article

A Novel Botanical Combination Attenuates Light-Induced Retinal Damage through Antioxidant and Prosurvival Mechanisms

Correspondence should be addressed to Jun Du; eric.du@amway.com

Received 15 November 2019; Revised 25 December 2019; Accepted 1 February 2020; Published 14 March 2020

Academic Editor: Francisco J. Romero

Copyright © 2020 Juntao Kan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

在全世界范围内，光引起的眼疲劳变得越来越普遍。现代社会迫切需要有效的视网膜光损伤治疗方案。我们研究了由叶黄素酯、玉米黄质、菊花、枸杞和黑加仑提取物组成的新配方对视网膜损伤的影响。本研究中，我们同时诱导了体内和体外导致的视网膜光损伤模型。

The prevalence of light-induced eye fatigue is increasing globally. Efficient regimen for mitigating light-induced retinal damage is becoming a compelling need for modern society. We investigated the effects of a novel combination of lutein ester, zeaxanthin, zephyranthemin, goji berry, and black currant extracts against retinal damage. In the current work, both in vitro and in vivo light-induced retinal damage models were employed. Animal study showed that under strong light exposure (15000 lx for 2 hours), the a-wave and b-wave from electroretinogram were significantly decreased. Treatment with the combination significantly restored the decrease for b-wave under high- and low-stimulus intensity. Histological analysis reported a substantial decrease in the outer nuclear layer (ONL) thickness in the model group, while the supplementation with the combination significantly improved the ONL thickness. To further explore the underlying mechanism of the protective effects, we utilized ARPE-19 retinal pigment epithelial cell line and found that strong light stimulation (2900 lx for 30 minutes) significantly increased phosphorylation of p38 and JNK and decreased HIF expression. Intriguingly, chrysanthemum, black currant extracts, lutein ester, and zeaxanthin significantly decreased the phosphorylation of p38 and JNK, while chrysanthemum, goji berry, black currant extracts, and lutein ester restored HIF expression. The botanical combination can alleviate light-induced retina damage potentially through antioxidant and prosurvival mechanisms.

通过抗氧化和促生存机制，我们的植物配方可以缓解视网膜的光损伤。

该论文发表于国际营养学期刊《氧化医学和细胞寿命》第 2020 卷 | 第 7676818 条整篇论文请去安利头条 App—下载专区下载